Understanding VUR grade 1 and its treatment options
What is VUR grade 1?
VUR grade 1 is the mildest form of VUR. Urine enters the ureter but does not travel all the way up to the kidney. The ureters look normal in size.
VUR grade 1
The likelihood of spontaneous resolution varies according to a child’s age, grade of VUR, and whether the VUR is on one ureter or both.
VUR Resolution Chart – Percent Chance of Reflux Resolution After A Specified Number of Years1
American Urological Association
| 1 Year | 2 Years | 3 Years | 4 Years | 5 Years | |
| Grade 1 | 39.3% | 63.1% | 77.6% | 86.4% | 91.8% |
More severe grades of reflux are associated with lower rates of spontaneous resolution and a higher incidence of renal scarring.2
VUR treatment options
There are basically four ways your child’s pediatric urologist or doctor may decide to treat your child, depending on the severity of your child’s VUR. The higher the grade, the more likely that treatment is needed. VUR treatment options are dependent on the grade but vary from watchful waiting, antibiotics, endoscopic treatment with Deflux, or surgery.3
Deflux is indicated for the treatment of children with VUR grades 2-4.
Resources:
References:
- Elder JS, Peters CA, Arant BS Jr, et al. Pediatric vesicoureteral reflux guidelines panel summary report on the management of primary vesicoureteral reflux in children. J Urol. 1997;157(5):1846-1851.
- Baskin LS, Kogan BA, Stock JA. Handbook of Pediatric Urology Third Edition. Philadelphia, PA: Wolters Kluwer; 2019.
- Peters CA, Skoog SJ, Arant BS Jr, et al. Summary of the AUA guideline on management of primary vesicoureteral reflux in children. J Urol. 2010;184(3):1134-1144.
